| Authors | Zeinab Yaghoobi Alireza Safahieh, Mohammad Taghi Ronagh, Ali Movahedinia, Seied Mohammad Mousavi |
|---|---|
| Journal | Comparative Clinical Pathology |
| Page number | 1305-1313 |
| Serial number | 26 |
| IF | 0.91 |
| Paper Type | Full Paper |
| Published At | 1-1-2017 |
| Journal Grade | ISI |
| Journal Type | Typographic |
| Journal Country | Iran, Islamic Republic Of |
| Journal Index | SJR |
Abstract
Bisphenol A (BPA) is one of the industrial chemical
compounds which is produced in large volume throughout the
world. It is a monomeric compound that is used in the manufacture
of polycarbonate plastics and epoxy resins. The widespread
use of BPA and its entry to aquatic ecosystems are
serious problems. The aim of this study is to assess the change
in the hematological parameters of Acanthopagrus latus as
biomarkers after exposure to BPA in low concentrations at
1, 5, 10, and 50 (μg/g BPA). The experimental period was
21 days, and the injections were conducted in 0, 7, and 14 days
in complete dose form. The blood collection from fishes was
carried out in 14 and 21 days. Hematological profile, including
red blood cells (RBCs), hematocrit (Ht), hemoglobin (Hb),
MCH, MCV, MCHC, and white blood cell differential counts
(lymphocytes, monocytes, basophils, eosinophils, and neutrophils)
was conducted. The results of this study indicated that
BPA has an inverse correlation with fish hematological parameter
abnormalities; increasing concentration of BPA leads
to a decrease in the RBC, Ht, Hb, secondary indices, and
lymphocytes. Therefore, it was concluded that all the studied
hematological parameters can be used as biomarkers for the
presence of xenobiotic such as BPA in the natural
environment.