Hematological changes in yellowfin seabream (Acanthopagrus latus) following chronic exposure to bisphenol A

چکیده مقاله

Bisphenol A (BPA) is one of the industrial chemical

compounds which is produced in large volume throughout the

world. It is a monomeric compound that is used in the manufacture

of polycarbonate plastics and epoxy resins. The widespread

use of BPA and its entry to aquatic ecosystems are

serious problems. The aim of this study is to assess the change

in the hematological parameters of Acanthopagrus latus as

biomarkers after exposure to BPA in low concentrations at

1, 5, 10, and 50 (μg/g BPA). The experimental period was

21 days, and the injections were conducted in 0, 7, and 14 days

in complete dose form. The blood collection from fishes was

carried out in 14 and 21 days. Hematological profile, including

red blood cells (RBCs), hematocrit (Ht), hemoglobin (Hb),

MCH, MCV, MCHC, and white blood cell differential counts

(lymphocytes, monocytes, basophils, eosinophils, and neutrophils)

was conducted. The results of this study indicated that

BPA has an inverse correlation with fish hematological parameter

abnormalities; increasing concentration of BPA leads

to a decrease in the RBC, Ht, Hb, secondary indices, and

lymphocytes. Therefore, it was concluded that all the studied

hematological parameters can be used as biomarkers for the

presence of xenobiotic such as BPA in the natural

environment.